Red cell membrane

The red cell membrane is composed of:

Lipids:

Phospholipids: phosphatidylcholine; phosphatidylethanolamine; sphingomyelin; phosphatidylserine) Cholesterol

Proteins: Integral membrane proteins: Band 3 or anion exchange protein Glucose transporter GLUT 1

Glycophorins, which have a high sialic acid content

Cytoskeletal proteins (which form a dense two-dimensional fibrous network): Spectrin protein family: alpha and beta spectrins; spectrin deficiency is a hallmark of red cells in hereditary spherocytosis Ankyrin

Short filaments of F-actin Proteins 4.1, 4.2 and 4.9 p55

Adducins

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