Signal transduction

Signal transduction refers to the mechanism of initiation of a cellular response after an agonist binds to a receptor. The extracellular signal initiates an intracellular signalling cascade that transfers, transforms, amplifies and then distributes it. The mechanisms of signal transduction include:

Membrane depolarisation induced by the opening of a ligand-gated ion channel: neurotransmitters, amino acids;

Activation of a G-protein (guanidine nucleotide-binding protein): peptides, neurotransmitters, prostaglandins; Synthesis of a second messenger

Cyclic nucleotide: adenosine 3'-5'-monophosphate (cyclic AMP), guanosine 3'-5'-monophosphate (cyclic GMP)

Intermediates of polyphosphoinositide metabolism: diacylglycerol (DAG), inositol-1,4,5-triphosphate (IP3) Calcium ions

A protein phosphorylation cascade that activates or inhibits intracellular enzymes leading to changes in target cell activity.

Was this article helpful?

0 0
Tips and Tricks For Boosting Your Metabolism

Tips and Tricks For Boosting Your Metabolism

So maybe instead of being a pencil-neck dweeb, youre a bit of a fatty. Well, thats no problem either. Because this bonus will show you exactly how to burn that fat off AS you put on muscle. By boosting your metabolism and working out the way you normally do, you will get rid of all that chub and gain the hard, rippled muscles youve been dreaming of.

Get My Free Ebook

Post a comment