YsCharacteristics of hepatocytes

o * Polarised epithelial cells bounded by three distinct membrane domains:

Sinusoidal, or basolateral, membrane, oriented along the sinusoids and lined with microvilli. This allows active and bidirectional transport of proteins, water, organic solutes. Apical, or bile canalicular, membrane, which are joined by tight junctions to form canaliculi, long and narrow channels less than 1 mm in diameter. This maintains canalicular shape and is involved in bile formation. Lateral hepatic membrane, between adjacent hepatocytes. This contains structural proteins that allow attachment and communication between cells. Tight junction complexes separate the sinusoidal space from the bile canaliculi.

* Arranged in cords on a basement membrane in the liver lobule.

* Possess highly developed endoplasmic reticulum, mitochondria, peroxisomes, lysosomes, Golgi complex and cytoskeleton.

* The liver microsomal fraction comprises the smooth and rough endoplasmic reticulum and the Golgi complex.

Was this article helpful?

0 0
Wake Up Now

Wake Up Now

For Those Who Can’t Wake Up On Time And Fatigue Throughout The Day. Now You Can Wake Up Early And Be Super Energetic Everyday.

Get My Free Ebook

Post a comment