Blood Transfusion in Medicine II Bone Marrow Transplantation

Blood transfusion support is essential to the successful outcome of bone marrow transplantation, and the presence of a bone marrow transplant unit in an institution will likely account for a large percentage of total platelet usage. Bone marrow transplantation is more correctly termed "stem cell transplantation", since there are several sources of hematopoietic progenitor cells (HPC). Traditionally, HPC have been collected by large volume aspiration of bone marrow under anesthesia (1-2 liters). In the last fifteen years, there has been increasing interest in collecting HPC from peripheral blood, initially for autologous, and more recently, for allogeneic transplantation. Newer sources of stem cells are umbilical cord blood; fetal hepatocytes may prove useful in the future. At this time, much interest is focusing on peripheral blood and umbilical cord blood as sources of HPC.

Stem cell transplantation is best divided into the autologous and allogeneic, since transfusion requirements and considerations differ.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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