Courselife expectancy

Inclusion: In SMA type I and II, there is an arrest of development of motor milestones. Children with SMA type I are never able to sit without support. Children with SMA type II are unable to stand or walk without aid. In SMA type III, the ability to walk will be achieved.

Inclusion: In SMA type I, the majority of patients have a life expectancy less than 2 years. In SMA type II, survival into adolescence or adulthood is common. In SMA type III, life expectancy is most likely normal.

Comment: There will be certain patients who do not clearly fit any one category.

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