Munchausen Syndrome By Proxy

Brain Power Genesis

Natural Dementia Cure and Treatment

Get Instant Access

Generally a pediatric diagnosis, Munchausen syndrome by proxy (MSBP) may be diagnosed both by inclusion and by exclusion. Table 57 identifies the specific criteria to be followed. Unfortunately,

Table 51

Neuropathological Subtypes in Frontotemporal Dementia

1. When the predominant neuropathological abnormalities are tau-positive inclusions (with associated neuron loss and gliosis), and insoluble tau has a predominance of tau with three microtubule-binding repeats, the most likely diagnoses are as follows:

a. Pick's disease.

b. Frontotemporal dementia with Parkinsonism linked to chromosome 17.

c. Other as-yet-unidentified familial and sporadic frontotemporal disorders.

2. When the predominant neuropathological abnormalities are tau-positive inclusions (with associated neuron loss and gliosis), and insoluble tau has a predominance of four microtubule-binding repeats, the most likely diagnoses are as follows:

a. Corticobasal degeneration.

b. Progressive supranuclear palsy.

c. Frontotemporal dementia with Parkinsonism linked to chromosome 17.

d. Other as-yet-unidentified familial and sporadic frontotemporal disorders.

3. When the predominant neuropathological abnormalities are tau-positive inclusions (with associated neuron loss and gliosis), and insoluble tau has a predominance of three and four microtubule-binding repeats, the most likely diagnoses are as follows:

a. Neurofibrillary tangle dementia.

b. Frontotemporal dementia with Parkinsonism linked to chromosome 17.

c. Other as-yet-unidentified familial and sporadic frontotemporal disorders.

4. When the predominant neuropathological abnormalities are frontotemporal neuronal loss and gliosis without tau- or ubiquitin-positive inclusions and without detectable amounts of insoluble tau, the most likely diagnoses areas follows:

a. Frontotemporal lobar degeneration (also known as dementia lacking distinct histopathological features).

b. Other as-yet-unidentified familial and sporadic frontotemporal disorders.

5. When the predominant neuropathological abnormalities are frontotemporal neuronal loss and gliosis with ubiquitin-positive, tau-negative inclusions and without detectable amounts of insoluble tau, with motor neuron disease (MND) or without MND but with MND-type inclusions, the most likely diagnoses areas follows:

a. Frontotemporal lobar degeneration with MND.

b. Frontotemporal lobar degeneration with MND-type inclusions but without MND.

c. Other as-yet-unidentified familial and sporadic frontotemporal disorders.

Adapted from McKhann GH, Albert MS, Grossman M, Miller B, Dickson D, Trojanowski JQ. Clinical and pathological diagnosis of frontotemporal dementia: report of the work group on frontotemporal dementia and Pick's disease. Arch Neurol 2001;58:1803-1809.

Table 52

Consensus Diagnostic Criteria for Frontotemporal Lobar Degeneration

List 1: the clinical diagnostic features of frontotemporal dementia Clinical profile

Character change and disordered social conduct are the dominant features initially and throughout the disease course. Instrumental functions of perception, spatial skills, praxis, and memory are intact or relatively well preserved. I. Core diagnostic features:

A. Insidious onset and gradual progression.

B. Early decline in social interpersonal conduct.

C. Early impairment in regulation of personal conduct.

D. Early emotional blunting.

E. Early loss of insight.

II. Supportive diagnostic features: A. Behavioral disorder:

1. Decline in personal hygiene and grooming.

2. Mental rigidity and inflexibility.

3. Distractibility and impersistence.

4. Hyperorality and dietary changes.

Table 52 (Continued)

Was this article helpful?

0 0
Unraveling Alzheimers Disease

Unraveling Alzheimers Disease

I leave absolutely nothing out! Everything that I learned about Alzheimer’s I share with you. This is the most comprehensive report on Alzheimer’s you will ever read. No stone is left unturned in this comprehensive report.

Get My Free Ebook


Post a comment