Takayasu's arteritis is a rare (one to two cases per million per year) inflammatory of medium- and large-sized arteries, with a strong predilection for the aortic for the aortic arch and its branches. It is also known as "aortic arch syndrome." It most often affects young women, and is found worldwide.
Pathologically there is a panarteritis with mononuclear infiltrates and sometimes giant cells. There may be stenosis and vessel occlusion with or without thrombosis. It may present as a nonspecific systemic illness, or with symptoms related to stenosis or occlusion of the aorta, its branches, or pulmonary arteries. Pulses are commonly absent in the involved vessels, particularly the subclavian artery. The diagnosis of Takayasu's arteritis should be suspected strongly in a young woman who develops a decrease or absence of peripheral pulses, discrepancies in blood presure, and arterial bruits. Table 12 lists diagnostic criteria from the American Rheumatological Association. Treatments include glucorti-coids, angioplasty of affected arteries, and control of hypertension leading to organ injury.
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...