Breast Cancer Adjuvant Therapy

Chemotherapy is traditionally initiated six weeks postoperatively. This allows the tissue time to heal prior to the immunosuppression associated with chemotherapy. Chemotherapy was historically reserved for patients with a poor prognosis. This included patients with greater than 4 positive nodes, primary tumors greater than 4 cm, a grade III tumor, or any tumor with lymphatic or vascular invasion. All of these imply systemic spread of tumor. Neoadjuvant chemotherapy is used in women who desire...

Intradermal Radiocolloid Injection

Current recommended guidelines for performance ofradioguided sentinel lymphnode biopsy include intradermal injection of 0.5 mCi of 0.2 micron filtered technetium-99 sulfur colloid in a volume of 6 mL at least 1 h prior to operation. For intradermal injection, filtered technetium sulfur colloid is injected in four or five locations into the skin raise a wheal overlying the tumor. For tumor locations in which it is not possible to identify the area of skin overlying the tumor, peritumoral...