Fresh Frozen Plasma FFP

FFP is produced from the separation of plasma from donated whole blood. It is subsequently stored at -18°C and has a shelf life of up to 1 year. Each unit contains about 400 mg of fibrinogen and 1 unit activity of each of the clotting factors. The most labile clotting factors (V and VIII) may be diminished proportional to shelf life. Once thawed, it can be stored for up to 24 hours before it must be discarded.

Its primary uses include:

1. Replacement of clotting factors for deficiency

2. Massive transfusion bleeding diathesis

3. Antithrombin III deficiency

4. Reversal of warfarin effect

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