Needle Biopsy

Transthoracic fine needle aspiration (TFNA) can be used to obtain a diagnosis; however a benign or indeterminate result is not exclusive owing to a high false negative rate. TFNA is generally reserved for poor operative candidates for thoracotomy who require a diagnosis for alternative treatment. There is a 30% rate of pneumothorax following biopsy.

Mediastinoscopy can be used to evaluate suspicious mediastinal nodes or provide a means of biopsy of centrally located lesions. For lesions in the aorticpulominary window, a Chamberlain procedure can be done to obtain a biopsy.

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