Other Hemostatic Agents

There are many other agents available to control minor bleeding.

Surgicel®. This is oxidized cellulose that reacts with blood to form a clot. It will absorb in 2-4 weeks. Surgicel® also has minimal bactericidal effect but delays wound healing.

Gelfoam®. This acts to absorb and promote imitation of coagulation. It is typically combined with thrombin.

Avitene®. This is a microcrystalline collagen that adheres to platelets to stimulate clotting.


1. Jackson MR. Fibrin sealants in surgical practice: An overview. Am J Surgery 2001; 182:1S-7S.

2. Morikawa T. Tissue sealing. Am J Surgery 2001; 182:29S-35S.

3. Rousou J, Gonzalez-Lavin L, Cosgrove 0 et al. Randomized clinical tria] of fibrin sealant in patients undergoing resternotomy or reoperation after cardiac operations. J Thoracic Cardiothoracic Surgery 1989; 97:194-203.

Suggested Reading

Jackson MR. Developing surgical techniques: The role of fibrin sealants. Am J Surgery 2001; Supplement.

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