Packed Red Blood Cells PRBC

Each unit of packed red blood cells (PRBC) contains approximately 450 mL of red blood cells with a small amount of plasma and anticoagulant. The hematocrit is usually around 60%. PRBC can be stored for 42 days. These concentrated solutions have most of the plasma and its constituents removed and therefore do not contain platelets, albumin or clotting factors.

Approximately 90% of transfusions are either allergic or febrile. This is most commonly due to antibodies directed against donor leukocytes; however it can be a sign of a transfusion reaction. Leukocytes in donor blood can be removed during transfusion with cotton or synthetic fiber filter. Some have suggested premedication with diphenhydramine and acetominiphen to diminish this reaction.

0 0

Post a comment