Sphincter of Oddi Dysfunction and Acute Idiopathic Pancreatitis

No obvious etiology is identifiable by history, laboratory tests, and standard imaging studies in 10% to 20% of patients with acute pancreatitis. Consensus has not been achieved to date on the optimal approach to the diagnostic evaluation of these patients. ERCP with sphincter of Oddi manometry in this patient population in may detect sphincter dysfunction and a possible cause of pancreatitis.

Symptoms improved in 83% of patients who were found to have elevated sphincter pressures compared to 33% of patients who had normal sphincter pressures. The complication rate of performing sphincterotomy in this patient population is real and is 20% to 40%.

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