BGlandular cell abnormalities

(1) Atypical glandular cells (AGC): may be endocervical, endometrial, or other glandular cells

(2) Endocervical adenocarcinoma in situ (AIS)

(3) Adenocarcinoma c. The LSIL category includes changes consistent with human papillomavirus (HPV), mild dysplasia, or CIN I (grade 1 cervical intraepithelial neoplasia). HSIL includes changes consistent with moderate or severe dysplasia, CIN II or III, and carcinoma in situ (CIS).

5. Hyperkeratosis or parakeratosis on an otherwise negative Pap smear is not a marker for significant CIN and may be related to infection or trauma with inflammation, such as from use of a diaphragm. The Pap smear should be repeated in 6 to 12 months.

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