Intrapartum antibiotic prophylaxis is recommended for the following

1. Pregnant women with a positive screening culture unless a planned Cesarean section is performed in the absence of labor or rupture of membranes

2. Pregnant women who gave birth to a previous infant with invasive GBS disease

3. Pregnant women with documented GBS bacteriuria during the current pregnancy

4. Pregnant women whose culture status is unknown (culture not performed or result not available) and who also have delivery at <37 weeks of gestation, amniotic membrane rupture for >18 hours, or intrapartum temperature >100!4°F (>38°C)

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