Mechanisms of action

1. The most important mechanism of action is estrogen-induced inhibition of the midcycle surge of gonadotropin secretion, so that ovulation does not occur.

2. Another potential mechanism of contraceptive action is suppression of gonadotropin secretion during the follicular phase of the cycle, thereby preventing follicular maturation.

3. Progestin-related mechanisms also may contribute to the contraceptive effect. These include rendering the endometrium is less suitable for implantation and making the cervical mucus less permeable to penetration by sperm.

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