Dose

a. Terbutaline is the most commonly used beta-agonist for labor inhibition. It is typically given as a continuous intravenous infusion started at 2.5 to 5 pg/min; increased by 2.5 to 5 pg/min every 20 to 30 minutes to a maximum of 25 pg/min, or until the contractions have abated. At this point, the infusion may be reduced by decrements of 2.5 to 5 pg/min to the lowest dose that maintains uterine quiescence.

b. Terbutaline can also be administered subcu-taneously as 0.25 mg every 20 to 30 minutes for up to four doses or until tocolysis is achieved. It should be withheld if the maternal heart rate exceeds 120 beats/min. Once labor is inhibited, 0.25 mg can be administered every 3 to 4 hours until the uterus is quiescent for 24 hours.

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