No atypia

a. Endometrial hyperplasia without atypia is evaluated initially by hysteroscopy and dilatation and curettage. If the diagnosis remains unchanged and an ovarian estrogen source is excluded, then treatment with continuous medroxyprogesterone acetate (MPA, Provera) 10 mg daily for three months can be initiated. A follow-up endometrial biopsy should be performed immediately after cessation of drug therapy.

2. With atypia. Endometrial hyperplasia with atypia is a premalignant condition, preferably treated with hysterectomy. Alternatively, continuous oral megestrol at doses of 40 mg two to four times per day can be administered after coexistent endometrial cancer is excluded. An endometrial biopsy should be performed after three months of therapy.

References: See page 184.

100 Pregnancy Tips

100 Pregnancy Tips

Prior to planning pregnancy, you should learn more about the things involved in getting pregnant. It involves carrying a baby inside you for nine months, caring for a child for a number of years, and many more. Consider these things, so that you can properly assess if you are ready for pregnancy. Get all these very important tips about pregnancy that you need to know.

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