Clinical Parameters
The most important clinical parameter is the stage of the disease, as discussed in Chapter 11 (1,2). TNM stages 1 and 2 do much better than stages with erythroderma or extracutaneous involvement stages 3 and 4.
Other prognostic parameters are ulceration of tumors (3), bone marrow involvement (4), size of atypical circulating cells (<11 nm, >11 nm) (5), and percentage of T cells in the peripheral blood (more or less than 55%) (6). Detection of a peripheral blood T-cell clone seems to be an independent prognostic marker in mycosis fungoides (7).
Demographic factors
Race
Occupation in manufacturing industry
Clinical parameters T-stages
Percentage of skin involvement
Ulceration of skin lesions
Involvement of lymph nodes and visceral organs
Bone marrow involvement
Peripheral blood involvement
Size of atypical circulating cells (nm)
Percentage of T cells in the peripheral blood
Oral manifestation
Histopathology
Cytomorphology
Nuclear volume (nm3)
Large cell lymphoma (LCL)
Cytological transformation
Tumor thickness
Granulomatous features
Hemophagocytosis
DNA cytophotometry
Immunophenotype

Curing Eczema Naturally
Do You Suffer From the Itching, Redness and Scaling of Chronic Eczema? If so you are not ALONE! It strikes men and women young and old! It is not just
Post a comment