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The distinction of three different histologic LyP types has so far not proven to be of clinical or prognostic significance and is thus not supported by all experts in the field.

Sometimes, the development of large nodules up to several centimeters in diameter is observed in LyP patients; they may last for months until spontaneous regression occurs (8). It is still a matter of debate whether such lesions should be considered as part of the spectrum of clinical manifestation of LyP, or whether those large nodular lesions rather represent concurrent CD30+ ALCL.

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