Differential Diagnosis

The differential diagnosis of primary cutaneous follicular lymphoma includes other B-cell lymphomas such as extranodal marginal zone B-cell lymphoma of MALT type. In this lymphoma, there are usually reactive lymphoid follicles surrounded by a heterogeneous cellular infiltrate composed of centrocyte-like cells, monocytoid B cells, plasma cells, lymphoplasmacytoid cells, and small lymphocytes. The plasma cells usually are monoclonal, immunophenotypic analysis reveals a light-chain restriction for kappa or lambda light chains (10). Some cases of cutaneous mantle-cell lymphoma may morphologically resemble a cutaneous follicular lymphoma. In contrast to follicular lymphoma, the neoplastic cells in mantle-cell lymphoma express CD5 and cyclin D1.

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Curing Eczema Naturally

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