Differential Diagnosis

The differential diagnostic spectrum for cutaneous IPT is quite broad, primarily because of the highly variable histological patterns. IPT differs from subcutaneous lymph nodes because it lacks subcapsular and medullary sinuses. The polyclonal nature of the infiltrate allows one to exclude a lymphoma. Angiolymphoid hyperplasia with eosinophilia and Kimura disease both have a more prominent vascular component and eosinophils. Infectious dermatoses (mycobacteria, deep fungal infections) are not well circumscribed, have large numbers of neutrophils, and often display pseudocarcinomatous hyperplasia. In addition, special stains may help to identify

Cutaneous inflammatory pseudotumor

Clinical features

Solitary, slowly growing, tender nodule Histological features

Well-circumscribed nodular infiltrates in deep dermis/subcutis with reactive germinal centers, plasma cells, eosinophils. Proliferation of spindle/stellate myofibroblasts, sclerotic stroma in later stages Immunophenotype

Polyclonal expression of k or l on plasma cells Spindle/stellate cells: SMA+ Treatment Excision Clinical course Benign a causative pathogen. The later stages of cutaneous IPT should be distinguished from erythema elevatum diutinum and granuloma faciale, both of which usually contain vasculitic changes. Dermatofibroma with lymphoid follicles and perivascular plasmacytosis differs from cutaneous IPT because the germinal centers are unevenly distributed and concentrated at the periphery of the infiltrate.

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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