Info

T1, limited lesions covering <10% of the skin surface. T2, generalized lesions covering 10% and more of the skin surface. T3, tumors, one or more. T4, generalized erythroderma.

N0, no palpable lymph nodes, pathology negative for CTCL.

N1, palpable peripheral lymph nodes, pathology negative for CTCL.

N2, no palpable peripheral lymph nodes, pathology positive for CTCL.

N3, palpable peripheral lymph nodes, pathology positive for CTCL.

M0, no involvement of visceral organs.

M1, involvement of visceral organs.

Source: From Ref. 4.

T1, limited lesions covering <10% of the skin surface. T2, generalized lesions covering 10% and more of the skin surface. T3, tumors, one or more. T4, generalized erythroderma.

N0, no palpable lymph nodes, pathology negative for CTCL.

N1, palpable peripheral lymph nodes, pathology negative for CTCL.

N2, no palpable peripheral lymph nodes, pathology positive for CTCL.

N3, palpable peripheral lymph nodes, pathology positive for CTCL.

M0, no involvement of visceral organs.

M1, involvement of visceral organs.

Source: From Ref. 4.

on a heterogenous qualitative and quantitative criteria (7,8). Involvement of peripheral blood is not a major criterion in this staging system even though recently included (9). Zackheim et al. (10) showed in a study with 489 patients that the relative survival of CTCL patients (MF and Sezary) worsens with increasing skin stage. The 10-year survival in T1 patients is comparable to that of the general population; in T2 patients, 67.4%; in T3 patients, 39.2%; and in T4 patients, 41%. The great majority (80-85%) of patients with CTCL do not die from their disease.

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