Treatment

Usually, no treatment is necessary due to the self-healing nature of the disease (7). CLINICAL COURSE AND PROGNOSIS

The disease follows a benign course with spontaneous regression of the lesions at the mean age of 9 years (1).

Benign cephalic histiocytosis

Clinical features Children under 3 years of age

Multiple, asymptomatic, papules with facial involvement Histological features

Medium-sized histiocytes with oval or irregular nuclei and eosinophilic cytoplasm Immunophenotype

Factor XIIIa+, CD68+, CD1a-, S-100-Treatment

Not required Clinical course and prognosis Benign with spontaneous regression

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