Treatment

Radiation therapy, chemotherapy, or surgery alone or in various combinations have been administered with good results (4,6,7).

Cutaneous T-cell-rich B-cell lymphoma

Clinical features

Elderly patients, male predilection Solitary nodules in head and neck region Histological features

Small lymphocytes and histiocytes (75-90%), few large cells (pleomorphic, immunoblasts,or centroblasts) Immunophenotype

Large cells: pan-B-cell antigens+, CD15-, CD30-Light chain restriction (not in all cases) Small cells: reactive T-helpers Molecular biology

IgH rearrangement in majority of cases Treatment

Radiation therapy, chemotherapy, or surgery Clinical course Unknown

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