Dimethylaminopropylamine

CAS Registry Number [109-55-7]

Dimethylaminopropylamine is an aliphatic amine present in amphoteric surfactants such as liquid soaps and shampoos. It is present as a residual impurity thought to be responsible for allergy from cocamidopropylbetaine. It is structurally similar to diethyl-aminopropylamine. It is also used as a curing agent for epoxy resins and an organic intermediate in chemical synthesises (ion exchangers, additives for flocculants, cosmetics and fuel additives, dyes and pesticides). Patch test has to be carefully interpreted, since the 1% aqueous solution has pH>11 (personal observation).

Suggested Reading

Angelini G, Foti C, Rigano L, Vena GA (1995) 3-Dimethylaminopropyl-amine: a key substance in contact allergy to cocamidopropylbetaine? Contact Dermatitis 32:96-99 Kanerva L, Estlander T, Jolanki R (1996) Occupational allergic contact dermatitis from 3-dimethylaminopropylamine in shampoos. Contact Dermatitis 35: 122-123 Speight EL, Beck MH, Lawrence CM (1993) Occupational allergic contact dermatitis due to 3-dimethylaminopropylamine. Contact Dermatitis 28:49-50

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