Propranolol

CAS Registry Number [525-66-6]

Propranolol is a beta-blocking agent that was responsible for the sensitization of workers in drug synthesis. In one case, epichlor-hydrin was used for the production of drugs propranolol and oxprenolol. Cross-reactivity is expected between beta-blockers.

Suggested Reading

Pereira F, Dias M, Pacheco FA (1996) Occupational contact dermatitis from propranolol, hydralazine and bendroflumethiazide. Contact Dermatitis 35:303-304

Rebandel P, Rudzki E (1990) Dermatitis caused by epichlorhydrin, Oxprenolol hydrochloride and propranolol hydrochloride. Contact Dermatitis 23: 199

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