Atrophoderma of Pasini and Pierini

Synonym(s)

Idiopathic atrophoderma of Pasini and Pierini; atrophodermia idiopatica progres-siva

Definition

Asymptomatic atrophy of the skin characterized by single or multiple, defined, depressed areas of skin

Pathogenesis

Possibly an end result of morphea; possibly related to spirochete infection (in Europe)

Clinical manifestation

Presenting as asymptomatic, slightly ery-thematous plaque or plaques on the trunk; lesions developing slate-gray to brown pigmentation, sharp peripheral border, and central depression

Differential diagnosis

Morphea; lichen sclerosus; skin atrophy from steroid injection; anetoderma; post-inflammatory hyperpigmentation

Therapy

Doxycycline; amoxicillin; hyperpigmenta-tion component: Q-switched alexandrite laser

References

Buechner SA, Rufli T (1994) Atrophoderma of Pasini and Pierini. Clinical and histopathologic findings and antibodies to Borrelia burgdorferi in thirty-four patients. Journal of the American Academy of Dermatology 30(3^441-446

0 0

Post a comment