Azole antifungal agents

Trade name(s)

Generic in parentheses: Exelderm (sulconazole); Lamisil AT (terbin-afine); Lotrimin; Mycelex (clotrimazole); Micatin (miconazole); Nizoral (ketocona-zole); Oxistat (oxiconazole); Spectazole (econazole)

Generic available

Drug class

Azole antifungal agents Mechanism of action

Cell wall ergosterol inhibition secondary to blockade of i4a-demethlyation of lanos-terol

Dosage form

Cream; solution; lotion

Dermatologic indications and dosage

See table

Common side effects

Cutaneous: skin eruption, pruritus

Serious side effects

None

Drug interactions

None

Contraindications/precautions

Hypersensitivity to drug class or component

References

Weinstein A, Berman B (2002) Topical treatment of common superficial tinea infections. American Family Physician 65(i0):2095-2i02

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