Balanitis xerotica obliterans

Synonym(s)

Lichen sclerosus of the penis; male genital lichen sclerosus; lichen sclerosus et atrophi-cus of the penis; penile lichen sclerosus

Bannayan-Riley-Ruvalcaba syndrome

Definition

Chronic, progressive, sclerosing, inflammatory dermatosis of the penis and prepuce

Pathogenesis

Unknown; minor relationship with autoimmune disorders

Clinical manifestation

Presents with soreness, burning sensation, mild erythema and hypopigmentation; as disease progresses, single or multiple discrete erythematous papules or macules coalescing into atrophic ivory, white, or purple-white patches or plaques, which may erode; possible development of vesiculation; possible phimosis occurring in uncircumcised men; occasional signs of lichen sclerosus at other skin sites

Differential diagnosis

Plasma cell balanitis; candidiasis; lichen planus; psoriasis; vitiligo; Reiter syndrome; erythroplasia of Queyrat

Therapy

Surgical therapy: circumcision; laser vaporization

Medical therapy: superpotent topical corticosteroids; testosterone propionate 1% ointment applied twice daily; acitretin

► Lichen sclerosus

References

Das S, Tunuguntla HS (2000) Balanitis xerotica obliterans - A review. World Journal of Urology i8(6):382-387

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