Clinical manifestation

Erythematous wheals, accompanied by a painful or burning sensation, which remain for several days; as lesions evolve, purpura may appear; lesions may resolve with postinflammatory pigmentation; associated photosensitivity, lymphadenopathy, arthralgia, angioedema, fever, abdominal pain, dyspnea, and pleural and pericardial effusions

Main identifiable causes: drug induced, such as angiotensin-converting enzyme inhibitors, penicillin, sulfonamides, fluoxet-ine, and thiazides; rheumatic diseases, such as lupus erythematosus and Sjogren syndrome; viral diseases, such as hepatitis B, hepatitis C, and infectious mononucleosis; hypocomplementemia occurs in patients with associated systemic diseases, such as systemic lupus erythematosus; regardless of cause, disease tends to run chronic cours

► Erythema toxicum

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