Clinical manifestation

Jadassohn-Lewandowsky type (PC-1): present at birth or from early childhood; thickened, brown-to-gray nail plates with rough surface; usually affects all fingers; toenails sometimes also involved; thickened fingernails may extend into periun-gual tissue, causing paronychia; circumscribed or diffuse hyperkeratoses of palms and soles; follicular hyperkeratosis on the face and on extensor aspect of proximal extremities; leukokeratosis of oral mucosa

Jackson-Lawler type (PC-2): thickened nail plates and other features of PC-1 type; natal teeth; unruly hair

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