Clinical manifestation

Cutaneous variant: secondary infection in burns or other trauma

396 Mucosal neuroma syndrome

Superficial variety: occurs in healthy people after trauma; vesicles, pustules, and plaques

Gangrenous variant: solitary, violaceous, painful, papule or plaque, with ecchymotic center; may ulcerate and disseminate; occurs in immunosuppressed patients Rhinocerebral variant: progressive orbital swelling and facial cellulitis, with discharge of black pus from the necrotic palatine or nasal eschars; proptosis; chemosis; ophthal-moplegia; blindness; decreased consciousness suggests spread to brain; non-specific gastrointestinal and pulmonary signs and symptoms

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