Clinical manifestation

Poorly defined areas of nonpitting edema, with sclerosis developing as disease progresses; skin surface becomes smooth and shiny, with loss of hair follicles and decreased ability to sweat; after months to years, skin softens and become atrophic Guttate variant: small, white, minimally indurated papules

Linear variant: discrete, indurated, linear, hypopigmented, sclerotic bands Frontoparietal linear morphea (en coup de sabre): linear, atrophic plaque, suggestive of a stroke from a sword, sometimes eventuating in hemifacial atrophy Progressive hemifacial atrophy (Romberg-Perry syndrome): primary lesion occurring in the subcutaneous tissue, muscle, and bone; dermis affected only secondarily and skin not sclerotic

Eosinophilic fasciitis: involves primarily the fascia; characterized by acute onset of painful, indurated skin, usually of the upper extremity, with orange-peel appearance and swelling of the affected extremity Diffuse variant: widspread hypopigmented, sclerotic plaques, often involving the upper trunk, abdomen, buttocks, and thighs

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