Clinical manifestation

Classic subtype: small, red papule or pustule evolving into deep ulceration; often arising at site of minor trauma, with violaceous undermined border; occurs most commonly on legs, but may be seen on any skin surface, including around stoma sites (peristomal pyoderma gangrenosum); intraoral ulcerated plaques (pyostomatitis vegetans), primarily in patients with inflammatory bowel disease Aytical subtype: vesiculopustular component only at the border, with erosion or superficial ulceration; most often occurs on dorsal aspect of hands, extensor surface of forearms or face

Pyoderma vegetans subtype: crusted, hyperplastic plaques without deep ulceration, similar to that seen in pyostomatitis vegetans; all subtypes may be associated with underlying polyarthritis, inflammatory bowel disease, myelogenous leukemia, or monoclonal gammopathy

Curing Irritable Bowel Syndrome

Curing Irritable Bowel Syndrome

Everyone has an upset stomach from time to time. You probably know the sort of thing I mean – sometimes you’ve got gas and at other times you feel queasy or nauseous. There may be times<br />when you can’t seem to go to the toilet for days, constipated as can be, but there are other days when diarrhea strikes and you can’t stop going!

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