Clinical manifestation

Classic subtype: small, red papule or pustule evolving into deep ulceration; often arising at site of minor trauma, with violaceous undermined border; occurs most commonly on legs, but may be seen on any skin surface, including around stoma sites (peristomal pyoderma gangrenosum); intraoral ulcerated plaques (pyostomatitis vegetans), primarily in patients with inflammatory bowel disease Aytical subtype: vesiculopustular component only at the border, with erosion or superficial ulceration; most often occurs on dorsal aspect of hands, extensor surface of forearms or face

Pyoderma vegetans subtype: crusted, hyperplastic plaques without deep ulceration, similar to that seen in pyostomatitis vegetans; all subtypes may be associated with underlying polyarthritis, inflammatory bowel disease, myelogenous leukemia, or monoclonal gammopathy

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