Clinical manifestation

Occurs on glans penis and scrotum in men, and labia minora, mons veneris, and fourchette in women; rare cervical involvement; soft, red papules or nodules arising at the site of inoculation; lesions eventually ulcerate and produce red, friable, granulo-matous plaques and nodules; ulcers with clean, friable bases and distinct, raised, rolled margins; autoinoculation results in lesions on adjacent skin; occasional hyper-trophic or verrucous plaques, with formation of large, vegetating masses resembling genital warts; swelling of the external genitalia in later-stage lesions

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