Dissecting cellulitis of scalp

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Synonym(s)

Dissecting cellulitis; perifolliculitis capitis abscedens et suffodiens; Hoffman's disease

Definition

Chronic inflammatory disease characterized by painful suppurating lesions of the scalp, leading to scarring alopecia

Pathogenesis

Associated with acne conglobata, hidraden-itis suppurativa, and pilonidal cysts, all of which have follicular blockage as the common mechanism; retained material dilates and causes follicular rupture; keratin and organisms from the damaged hair follicles initiate neutrophilic and granulomatous response; bacterial infection secondary event

Dove aerosol 191

Clinical manifestation

Perifollicular pustules; tender nodules (some discharging pus or gelatinous material); intercommunicating sinuses between nodules; patchy alopecia with scarring ; frequent recurrences over many years

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