Drug interactions

Barbiturates; beta agonists; COX-2 inhibitors; cyclosporine; digoxin; thiazide diuretics; glyburide/metformin; non-steroidal anti-inflammatory agents; phenytoin; rifampin; warfarin; many others

Prednisone. Dermatologic indications and dosage

Disease

Adult dosage

Child dosage

Acne vulgaris

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Acute febrile neutrophilic dermatosis

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Acute generalized exanthematous pustular dermatitis

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Acute graft versus host reaction

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Alopecia areata

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Aphthous stomatitis

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Atopic dermatitis

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Autoerythrocyte sensitization; erythema induratum

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Behcet's disease

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Brown recluse spider bite

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Bullous pemphigoid

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Churg-Strauss disease

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Cicatricial pemphigoid

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Contact dermatitis

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Dyshidrotic eczema

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Eosinophilic pustular folliculitis

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

0.5-2 mg per kg daily PO as a single AM dose for 7-21 days

Epidermolysis bullosa acquisita

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Epidermolytic hyperkeratosis

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Erythema annulare centrifugum

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Erythema gyratum

0.5-2 mg per kg daily PO as a single

0.5-2 mg per kg daily PO as a single

repens

AM dose

AM dose repens

AM dose

AM dose

476 Prednisone

Prednisone. Dermatologic indications and dosage (Continued)

Prednisone. Dermatologic indications and dosage (Continued)

Prednisone. Dermatologic indications and dosage (Continued)

Disease

Adult dosage

Child dosage

Papular mucinosis

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Paraneoplastic pemphigus

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Pemphigus vulgaris

1-2 mg per kg daily PO as a single AM dose

1-2 mg per kg daily PO as a single AM dose

Pityriasis lichenoides

0.5-2 mg per kg daily PO as a single AM dose

0.5-2 mg per kg daily PO as a single AM dose

Polymorphous light eruption

1 mg per kg PO as a single AM dose for 7-14 days

1 mg per kg PO as a single AM dose for 7-14 days

Post-herpetic neuralgia prophylaxis

1 mg per kg PO daily for 14-21 days

Not indicated

Pruritic papules and plaques of pregnancy

1 mg per kg PO as a single AM dose for 7-14 days

Not applicable

Psoriasis

1 mg per kg PO as a single AM dose for 7-14 days

1 mg per kg PO as a single AM dose for 7-14 days

Pyoderma gangrenosum

1 mg per kg PO as a single AM dose

1 mg per kg PO as a single AM dose

Sarcoidosis

20-40 mg daily PO for 2-3 months, followed by slow taper to 10 mg every other day for up to 1 year

10-30 mg daily PO for 2-3 months, followed by slow taper to 5 mg every other day for up to 1 year

Scabies 1 mg per kg PO as a single AM dose 1 mg per kg PO as a single AM dose

Scabies 1 mg per kg PO as a single AM dose 1 mg per kg PO as a single AM dose for 7-14 days for 7-14 days

Schnitzler syndrome 1 mg per kg PO daily for 14-21 days 1 mg per kg PO daily for 14-21 days

Seborrheic dermatitis 0.5-2 mg per kg daily PO as a single 0.5-2 mg per kg daily PO as a single

AM dose for 7-21 days AM dose for 7-21 days

Serum sickness

0.5-1 mg per kg PO daily for 7-21 days

0.5-1 mg per kg PO daily for 7-21 days

Stasis dermatitis

1 mg per kg PO as a single AM dose for 7-14 days

1 mg per kg PO as a single AM dose for 7-14 days

Stevens-Johnson syndrome

1 mg per kg PO daily for 14-21 days

1 mg per kg PO daily for 14-21 days

Sulzberger-Garbe syndrome

1 mg per kg PO daily as a single AM dose

1 mg per kg PO daily as a single AM dose

Temporal arteritis

1-2 mg per kg PO daily as a single AM dose

1-2 mg per kg PO daily as a single AM dose

Urticaria

1 mg per kg PO daily for no longer than 21 days; to be used only in severe, recalcitrant disease

1 mg per kg PO daily for no longer than 21 days; to be used only in severe, recalcitrant disease

Vogt-Koyanagi-Harada syndrome -iritis

1-2 mg per kg PO daily as a single AM dose

1-2 mg per kg PO daily as a single AM dose

for 7-14 days for 7-14 days

Schnitzler syndrome 1 mg per kg PO daily for 14-21 days 1 mg per kg PO daily for 14-21 days

Seborrheic dermatitis 0.5-2 mg per kg daily PO as a single 0.5-2 mg per kg daily PO as a single

AM dose for 7-21 days AM dose for 7-21 days

478 Pregnancy mask

Prednisone. Dermatologic indications and dosage (Continued)

Disease

Adult dosage

Child dosage

Weber-Christian

1-2 mg per kg PO daily as a single

1-2 mg per kg PO daily as a single

disease

AM dose

AM dose

Wegener's

1-2 mg per kg PO daily as a single

1-2 mg per kg PO daily as a single

granulomatosis

AM dose

AM dose

Xerotic eczema

0.5-1 mg per kg daily PO as a single AM dose for 7-10 days

0.5-1 mg per kg daily PO as a single AM dose for 7-10 days

Contraindications/precautions I

Hypersensitivity to drug class or compo- Pressure alopecia nent; systemic fungal infection; caution in patients with congestive heart failure, seizure disorder, hypertension, diabetes melli- ► Traction alopecia tus, tuberculosis; osteoporosis; impaired liver function

References

Williams LC, Nesbitt LT (2001) Update on systemic glucocorticosteroids in dermatology. Der-matologic Clinics 19(1)163-77

Pressure sore

► Decubitus ulcer

How To Deal With Rosacea and Eczema

How To Deal With Rosacea and Eczema

Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.

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