Drug interactions

Antifungal agents; barbiturates; car-bamazepine; carboplatin; cimetidine; cipro-

floxacin; colchicine; oral contraceptives; diltiazem; systemic corticosteroids; eryth-romycin; lovastatin; glyburide/metformin; metronidazole; nafcillin; non-steroidal anti-inflammatory agents; phenytoin; pimozide; potassium salts; pravastatin; protease inhibitors; rifampin; simvastatin; verapamil; vinca alkaloids

Cyclosporine. Dermatologic indications and dosage

Disease

Adult dosage

Child dosage

Alopecia areata

3-5 mg per kg PO daily, divided into

3-5 mg per kg PO daily, divided into

2 doses

2 doses

Atopic dermatitis

3-5 mg per kg PO daily, divided into

3-5 mg per kg PO daily, divided into

2 doses

2 doses

Behcet's disease

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Bullous pemphigoid

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Chronic actinic dermatitis

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Dermatomyositis

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Epidermolysis bullosa acquisita

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Hyperimmunoglobulin E 3 mg per kg daily for 6 months 3 mg per kg daily for 6 months syndrome

Hyperimmunoglobulin E 3 mg per kg daily for 6 months 3 mg per kg daily for 6 months syndrome

Lichen amyloidosis

3-5 mg per kg PO daily, divided into 2 doses

Not indicated

Lichen planus, erosive

Oral solution applied to erosions 3-4 times daily

Oral solution applied to erosions 3-4 times daily

Lupus erythematosus, acute

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Mycosis fungoides

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Pemphigus vulgaris

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Pityriasis rubra pilaris

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Psoriasis

3-5 mg per kg PO daily, divided into 2 doses

Not indicated

Pyoderma gangrenosum

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Reiter syndrome

3-5 mg per kg PO daily, divided into 2 doses

Not indicated

Relapsing polychondritis

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Scleroderma

3-5 mg per kg PO daily, divided into 2 doses

Not indicated

S├ęzary's syndrome

3-5 mg per kg PO daily, divided into 2 doses

3-5 mg per kg PO daily, divided into 2 doses

Urticaria

3-5 mg per kg PO daily for no longer than 3 months; to be used only for severe, recalcitrant disease

3-5 mg per kg PO daily for no longer than 3 months; to be used only for severe, recalcitrant disease

Cyclosporine. Dermatologic indications and dosage (Continued)

Disease Adult dosage Child dosage

Weber-Christian 3-5 mg per kg PO daily, divided into Not indicated disease 2 doses

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