Dyshidrotic eczema


Dyshidrosis; pompholyx; vesicular pal-moplantar eczema; vesicular eczema of palms and soles

Dyshidrotic eczema. Multiple vesicles on the hands, with concentration along the sides of the digits


Recurrent or chronic relapsing form of vesicular palmoplantar dermatitis


Occurring commonly in atopic individuals; associated with stress, infection, exogenous contactants, climate changes

Clinical manifestation

Symmetric crops of clear vesicles and/or bullae on the palms and lateral aspects of fingers and feet; vesicles deep seated, with a tapioca-like appearance, and sometimes becoming confluent to form bullae; may develop crusting, scaling, and fissuring after persistent scratching

Differential diagnosis

Contact dermatitis; vesicular tinea pedis; tinea manus; palmoplantar pustular psoriasis; autosensitization reaction (id reaction)


Corticosteroid, topical, high potency*; severe flare: prednisone; triamcinolone 4080 mg IM as single dose. Chronic persistent disease: azathioprine; local photochemotherapy; disulfiram 250500 mg PO per day in nickel-sensitive patients; aluminium acetate 5% solution soaks


Landow K (1998) Hand dermatitis. The perennial scourge. Postgraduate Medicine 103(1):141-142, 145-148, 151-152

196 Dyskeratoma, warty

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