Eccrine carcinoma

Synonym(s)

Eccrine adenocarcinoma; malignant tumor with eccrine differentiation

Definition

Neoplasm of eccrine sweat gland with potential for destructive local tissue infiltration and metastasis; sometimes subdivided into tumors arising de novo in normal skin and tumors originating from preexisting, benign, sweat gland tumors

198 Eccrine chromhidrosis

Pathogenesis

Derived from any portion of the eccrine apparatus or resulting from the malignant transformation of an existing benign eccrine tumor

Clinical manifestation

Non-specific solitary nodule or plaque with occasional ulceration, on the head, extremities, or trunk

Differential diagnosis

Basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; cutaneous metastasis; eccrine acrospiroma; micro-cystic adnexal carcinoma; eccrine porocar-cinoma; cutaneous adenoid cystic carcinoma

Therapy

Wide local excision; Mohs micrographic surgery; radiation therapy

References

Katzman BM, Caligiuri DA, Klein DM, DiMaio TM, Gorup JM (1997) Eccrine carcinoma of the hand: a case report. Journal of Hand Surgery -American Volume 22(4)737-739

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