Trade name(s)


Generic available

Drug class

Ornithine decarboxylase inhibitor Mechanism of action

Possibly related to ornithine decarboxylase inhibition, which decreases hair growth

Dosage form

13.9% cream

Dermatologic indications and dosage

See table

Common side effects

Cutaneous: stinging; burning sensation, irritant contact dermatitis, acneform eruption, pseudofolliculitis barbae

Serious side effects


Drug interactions



Hypersensitivity to drug class or component


Hickman JG, Huber F, Palmisano M (2001) Human dermal safety studies with eflornithine HCl 13.9% cream (Vaniqa), a novel treatment for excessive facial hair. Current Medical Research & Opinion 16(4)1235-244

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