Fifth disease, slapped-cheek disease, academy rash, Sticker's disease, Sticker disease
Childhood exanthem caused by human Par-vovirus B19, in which a 3-phased cutaneous eruption follows a mild prodrome
Parvovirus B19 viremia; production of specific immunoglobulin M (IgM) antibodies and subsequent formation of immune complexes; clinical findings probably result from the deposition of the immune complexes in the skin and joints
4-14 day incubation period; virus spreads primarily via aerosolized respiratory droplets
Mild prodromal phase, including headache, coryza, low-grade fever, pharyngitis, and malaise
First stage: erythema of the cheeks, with nasal, perioral, and periorbital sparing (slapped-cheek appearance) and fades over 2-4 days
Second stage: within 1-4 days of the facial rash, erythematous macular-to-morbilli-form eruption occurs primarily on the extremities
Third stage: after several days, most of the second stage eruption fades into a lacy pattern, particularly on the proximal extremities; lasts from 3 days to 3 weeks; after starting to fade, exanthem sometimes recurs over several weeks following exercise, sun exposure, friction, bathing in hot water, or stress; adults sometimes develop polyar-thropathy
acute rheumatic fever; allergic hypersensitivity reaction
Antihistamines, first generation, as sedative and mild anti-pruritic agent
Koch WC (2001) Fifth (human parvovirus) and sixth (herpesvirus 6) diseases. Current Opinion in Infectious Diseases i4(3):343-356
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Rosacea and Eczema are two skin conditions that are fairly commonly found throughout the world. Each of them is characterized by different features, and can be both discomfiting as well as result in undesirable appearance features. In a nutshell, theyre problems that many would want to deal with.