Erythema toxicum

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Erythema toxicum neonatorum; erythema neonatorum; toxic erythema; erythema neonatorum allergicum; erythema papulo-sum; urticaria neonatorum; erythema dys-pepsicum


Benign, self-limited eruption occurring primarily in healthy newborns in the early neonatal period



Clinical manifestation

Usual onset within the first 4 days of life in full-term infants, with peak onset occurring within the first 48 hours following birth; presents with a blotchy, evanescent, macular erythema, often on the face or trunk; sites of predilection include the forehead, face, trunk, and proximal extremities; mucous membranes usually spared

Differential diagnosis

Candidiasis; miliaria; pyoderma; insect bite reaction; varicella; herpes simplex virus infection; urticaria; folliculitis; transient neonatal pustular melanosis



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