Florid cutaneous papillomatosis

Synonym(s)

None

Definition

Disorder characterized by the rapid onset of numerous warty papules on the trunk and extremities, often in association with malignant acanthosis nigricans and/or sign of Leser-Trelet and an internal malignancy

Pathogenesis

Unknown

242 Florid papillomatosis of nipple ducts

Clinical manifestation

Multiple verrucous papules, beginning on the extremities, particularly on the dorsa of the hands and wrists; papules sometimes involve the entire body, including the face; usually associated with signs of internal cancer and malignant acanthosis nigricans and sign of Leser-Trelat

Differential diagnosis

Warts; acrokeratosis verruciformis of Hopf; seborrheic keratoses; epidermodysplasia verruciformis

Therapy

Treatment of underlying malignancy; topical therapies not effective

References

Schwartz RA (1993) Florid cutaneous papillomatosis. Clinics in Dermatology 11(1)189-91

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