Mechanism of action

DNA polymerase inhibition

Acyclovir. Dermatologic indications and dosage

Disease

Adult dosage

Child dosage

Eczema herpeticum

500 mg IV daily divided into 3 doses

15 mg per kg IV daily divided into

for 5 days

3 doses for 5 days

Herpes simplex virus 200 mg PO 5 times daily for 10 days 5 mg per kg IV 3 times daily for infection, 1st episode 5-10 days

Herpes simplex virus 400 mg PO twice daily for up to infection, prophylaxis 1 year

200 mg PO twice daily for up to 1 year

Herpes simplex virus 200 mg PO 5 times daily for 10 days 5 mg per kg IV 3 times daily for infection, 1st episode 5-10 days

Herpes simplex virus 400 mg PO twice daily for up to infection, prophylaxis 1 year

200 mg PO twice daily for up to 1 year

Herpes simplex virus 200 mg PO 5 times daily for 7 days 5 mg per kg IV 3 times daily for infection, recurrent 5-10 days

Herpes zoster 800 mg PO 5 times daily for 7 days 20 mg per kg PO 5 times daily for

7 days

Varicella 800 mg PO 5 times daily for 7 days 20 mg per kg PO 5 times daily for

7 days

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