Result of venous insufficiency; disturbed function of the deep venous plexus valvular system with backflow of blood from the deep to the superficial venous system, producing venous hypertension; possibly related to leukocyte sequestration in microcirculation, with increased contact of leukocytes with the capillary endothelium and

540 Steatoblepharon

Stasis dermatitis. Scaly, crusted, and eroded plaque on the lower extremity

release of inflammatory mediators; leukocyte sludging may block dermal capillaries, leading to tissue ischemia

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