Serious side effects

Dermatologie: anaphylaxis Gastrointestinal: hepatic failure

Ketoconazole. Dermatologic indications and dosage

Disease

Adult dosage

Child dosage

Eumycetoma

400 mg PO daily for months to years

Not established

Histoplasmosis

200-400 mg PO daily for 6-12 months

5-10 mg per kg PO daily for

6-12 months

North American blastomycosis

400-800 mg PO daily for a minimum of 6 months

5-7 mg per kg PO daily for 6 months

Protothecosis

200-400 mg PO daily for 2-6 weeks

Not established

South American blastomycosis

200-400 mg PO dailyfor 6-12 months

5-10 mg per kg PO daily for

6-12 months

Tinea versicolor

400 mg PO for 1 dose; repeat in 7 days

6.6 mg per kg PO for 1 dose; repeat in 7 days

Tinea versicolor

400 mg PO for 1 dose; repeat in 7 days

6.6 mg per kg PO for 1 dose; repeat in 7 days

Endocrine: adrenal insufficiency Laboratory: leukopenia, hemolytic anemia

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