Necrotic Keratinocytes

Lichen Striatus Histology

Cabanillas F, Armitage J, Pugh WC, et al. Lymphomatoid papulosis a T-cell dyscrasia with a propensity to transform into malignant lymphoma. Ann Intern Med 1995 122 3 210-217. 2. El-Azhary RA, Gibson LE, Kurtin PJ, et al. Lymphomatoid papulosis a clinical and histopathologic review of 53 cases with leukocyte immunophenotyping, DNA flow cytometry, and T-cell receptor gene rearrangement studies. J Am Acad Dermatol 1994 30 2 Pt 1 210-218. 3. Gellrich S, Wernicke M, Wilks A, et al. The cell...

Perivascular And Interstitial Dermatitis

Erythema Figuratum

B Perivascular and interstitial dermatitis without epidermal changes. C Lymphocytes and eosinophils perivascular and numerous neutrophils interstitial. Figure 1 A Urticae on the trunk. B Perivascular and interstitial dermatitis without epidermal changes. C Lymphocytes and eosinophils perivascular and numerous neutrophils interstitial. Figure 2 A Sharply demarcated purpuric erythema on the leg, a bulla Is seen in the uppermost part of the lesion. B Perivascular...

Malignant Follicular Tumors

Fibrofolliculoma Pathology

The major two malignant follicular tumors, pilomatrix carcinoma pilomatrical carcinoma and trichilemmocarcinoma trichilemmal carcinoma Fig. 23 have been discussed under their benign counterparts, pilomatrixoma and trichi-lemmoma respectively. Under the lumper philosophy, it has been proposed that both these are simply variants of squamous carcinoma, with shadow cells or clear cells being prominent features. 1. Hardisson D, Linaves MD, Cuevas-Santos J, Contreas F. Pilomatrix carcinoma a...

Vacuolar Interface Dermatitis

Relatively sparse inflammatory cell infiltrate that obscures the dermoepidermal junction Vacuolar alteration of basal keratinocytes necrotic keratinocytes Infiltrate may be only in the superficial dermis, or in both the superficial and deep dermis Clinical Presentation Erythema Multiforme Minor Acute, self-limited, recurrent disease of the skin and mucous membranes, most commonly in response to infection with herpes simplex virus types I and II Pleomorphic eruption with erythematous and...

Intradermal Nevus Fibrosis

Giant Congenital Melanocytic Nevus

Clark WH Jr, Elder DE, Guerry D IV, et al. A study of tumor progression the precursor lesions of superficial spreading and nodular melanoma. Human Pathol 1984 15 1147-1165. 2. Elder DE. The dysplastic nevus. Pathology 1985 17 291-297. 3. Barnhill RL, Roush GC, Duray PH. Correlation of histologic and cytoplasmic features with nuclear atypia in atypical dysplastic nevomelanocytic nevi. Hum Pathol 1990 21 51-58. 4. Piepkorn MW. An appraisal of the dysplastic nevus syndrome concept. Adv Dermatol...

Nodular And Diffuse Dermatitis

Nodular and diffuse dermatitis represents a group of diverse inflammatory conditions, each of which presents with inflammatory cells present in nodules filling portions of the dermis or diffusely filling the entire dermis. As with all inflammatory patterns, there is significant overlap between nodular dermatitis and diffuse dermatitis many of the same diseases may present with either pattern. Similarly, cutaneous inflammatory conditions which are most often superficial or superficial and deep...