Egi

Sorbitol AGE

... Thickening of

Swelling capillary wall

Vessel narrowing Ischemia

Vessel proliferation Bleeding

Normal fundus

Retinopathy (loss of vision)

I— C. Night Blindness and Color Blindness

Photo: Hollwich F. Taschenatlas der Augenheilkunde. 3rd ed. Stuttgart: Thieme; 1987

Vitamin A deficiency all-trans-vitamin A ^ * \

11-cis-vitamin A

Red blindness Green blindness (protanopia) (deuteranopia)

11-cis-retinal

Meta-rhodopsin

Rhodopsin \ i

Light perception ^

Red blindness Green blindness (protanopia) (deuteranopia)

Meta-rhodopsin

2 15-o h

\

0 0

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